CR5/CCL5 axis is linked to a poor outcome, and inhibition reduces metastasis in oral squamous cell carcinoma

García, IsaacIsaacGarcíaWilfredo Alejandro González‐ArriagadaRicardo D. ColettaCarlo Lozano‐BurgosC.M. GarciaJaime MaripillánFrancisca Alcayaga‐MirandaBastián Godínez-PachecoSebastián Oyarce-PezoaRene Flores2025-08-252025-08-252023-10-1310.1007/s00432-023-05443-1https://cris-uv.scimago.es/handle/123456789/4532WOS:001082777100001The CCR5/CCL5 axis is essential for interactions between malignant cells and microenvironment components, promoting tumor progression in oral squamous cell carcinoma (OSCC). This study aims to evaluate the association of CCL5 and CCR5 with the behavior of oral cancer and assess the therapeutic potential of a CCR5 antagonist.enacceso restringidoMaravirocCCR5 receptor antagonistCCL5CR5/CCL5 axis is linked to a poor outcome, and inhibition reduces metastasis in oral squamous cell carcinomajournal-article