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CR5/CCL5 axis is linked to a poor outcome, and inhibition reduces metastasis in oral squamous cell carcinoma
ISSN
0171-5216
Date Issued
2023-10-13
WoS ID
WOS:001082777100001
Abstract
The CCR5/CCL5 axis is essential for interactions between malignant cells and microenvironment components, promoting tumor progression in oral squamous cell carcinoma (OSCC). This study aims to evaluate the association of CCL5 and CCR5 with the behavior of oral cancer and assess the therapeutic potential of a CCR5 antagonist.
OCDE Subjects
Author(s)
Wilfredo Alejandro González‐Arriagada
Ricardo D. Coletta
Carlo Lozano‐Burgos
C.M. Garcia
Jaime Maripillán
Francisca Alcayaga‐Miranda
Bastián Godínez-Pacheco
Sebastián Oyarce-Pezoa
Rene Flores